by Evonik Health Care | November 2023

Can pharmaceutical manufacturing become more sustainable while maintaining strict safety standards? In this interview, Eric Neuffer discusses the adoption of sustainable practices such as waste reduction, using renewable energy sources, adopting green energy principles, and investing in research and development of sustainable technologies.  

by Dr. Maaike Everts | November 2023

This article discusses the significance of formulation development, cGMP manufacturing and aseptic filling challenges, which must all be overcome before the potential of recent imporvements of humen genome can be fully commercialized.

by Dr. Martin Schilling | October 2023

L-Tyrosine is an important amino acid for protein synthesis and cellular metabolism, however L-Tyrosine is not readily soluble. In this article, Dr. Martin Schilling discusses how replacing L-Tyrosine with dipeptides can enhance the solubility for free L-Tyrosine at neutral pH.  

by Jay Natarajan | October 2023

Those who think that liposomes and lipid nanoparticles (LNPs) are interchangeable terms for the same drug delivery technology would be wrong. Key differences exist not only in their target applications, but their actual morphology, composition and manufacturing process. In this interview with Dr. Jay Natarajan, one of Evonik’s formulation and manufacturing experts for LNPs and liposomes, some of these differences are reviewed.

by Dr. Martin Schilling | October 2023

Highly potent APIs are estimated to make up approximately one quarter of all new pharmaceutical entities. In this article, we explain why toxicological evaluation is important at every stage of HPAPI development and manufacturing and how experienced CDMOs ensure new life-saving treatments are brought to market safely.

by Dr. Martin Schilling | September 2023

L-Glutamine is used by practically all human and animal cells as a carbon source for growth and as a building block for proteins. In this article, Dr. Martin Schilling talks through approaches to stabilize L-Glutamine against chemical degradation in cell culture media applications.  

by Mahrokh Dadsetan, Jian-Feng Zhang, Cécile Boudot and Caroline Lauret | July 2023

Dentistry and periodontal surgery have been at the forefront of the development and use of bioresorbable biomaterials for several decades. This article discusses the exciting future prospects for bioresorbable dental devices.

by Dr. Martin Schilling | July 2023

Cell culture media used in biopharmaceutical production have come a long way over the last few decades. In this interview Dr. Martin Schilling highlights the key solubility, stability and other challenges that still face many media developers and biopharma companies.

by Felix Hofmann, Nina Hauschildt, Miriam Robota | July 2023

The process of applying coatings to pharmaceutical tablets is complex, involving many variables – and any problems in the process have the potential to impact the quality of the end product. In this article, we talk about what can go wrong during the coating process and outline helpful troubleshooting strategies. 

by Caroline Lauret | June 2023

A person’s skin can often give an indication of their overall well-being and health. Biomaterial technologies used for treating wounds, scars and to counteract skin aging have progressed rapidly in recent years. This article examines two aspects of sustainable skin self-healing: the use of non-animal-derived collagen for tissue regeneration, and the use of bioresorbable polymer powders to stimulate the body’s natural collagen production.

by Dr. Martin Schilling | June 2023

L-Cysteine and its oxidized form L-Cystine are essential amino acids used in cell culture and are present in all chemically defined media formulations. In this article, Dr. Martin Schilling describes how L-Cystine peptides can boost Cys-solubility and performance in cell culture media applications. 

by Nina Hauschildt, Miriam Robota | June 2023

Formulation design can make or break an oral drug product, and striking the right balance between functionality, performance and solubility is vital for its success. This article discusses the intricacies of formulation design and gives helpful tips to boost performance and accelerate speed to market of an oral drug product. 

by Nina Hauschildt & Miriam Robota | May 2023

For more than 70 years, innovations in the complex oral drug product industry have formed the foundation of modern medicine in a variety of applications. This article describes the role of functional polymers in the ability to control a drug’s release profile.

by Dr. Martin Schilling | May 2023

Cell culture processes are the technological foundation of the biopharmaceutical industry. The continued revolution in health care, driven by biological drugs has raised the importance of high-performing cell culture for the biopharmaceutical industry. This article is about how biopharmaceutical companies can ensure productivity, supply security, quality and consistency in their cell culture processes.

by Dr. Martin Schilling | April 2023

Chemically defined amino acids and their derivatives are often the preferred choice for use as components in cell culture media for biopharmaceuticals and vaccines. In this article, Dr. Martin Schilling discusses how dipeptides are evolving to match the performance, quality and processing needs of biopharma. 

by Andrea Engel |  March 2023

Evonik has just entered into a new collaborative research project to investigate new materials for RNA-based medicines. The three-year project is funded by the German Federal Ministry of Economic Affairs and Climate Action, who will support the research  with a two-digit million-euro sum. Find out more in this interview with Andrea Engel, head of Health Care growth projects at Evonik. 

by Yiming Ma |  June 2022

Spray-dried dispersion, hot-melt extrusion and solubilizing excipients are the most common techniques for solubility enhancement, but the pharmaceutical sector needs new innovations to maximize amorphous solid dispersion benefits. In this article, Yiming Ma discusses how microparticles can offer a potential extra avenue for successful solubility enhancement.

by Tom Tice & Whitney Moro | May 2022

Functional lactide/glycolide polymers play a key role in complex parenteral drug delivery products. In this article, two Evonik experts discuss the history and significance of polymer drug delivery, and what needs to be considered when formulating long-acting injectables.

Interview with Jochen Becker | February 2022

As the human impact on our environment continues to increase, all industries will need to act to reduce their environmental footprint, improve sustainability and live within the boundaries of our planet. In this interview, Jochen Becker talks about what this means for pharmaceutical manufacturing.  

Interview with Uwe Beekmann | April 19, 2022
MD+DI

Biosynthetic cellulose is a nature-identical material that is bioengineered by bacteria. In this article, Evonik’s Uwe Beekmann discusses the applications of this versatile material in wound dressings, implantable materials and drug delivery systems.

Interview with Jay Stone | April 2022

Many excipients are opening exciting opportunities for drug developers. One area of interest is the lipid drug delivery platforms used for transporting mRNA and nucleic acids. In this special report, experts from a range of companies provide their insight into how excipients are being used to support the APIs of today and tomorrow.

Interview with Thiago Borges | March 24, 2022

In this article on the application of additive manufacturing in complex orthopedic implants and components, Sam Brusco, Associate Editor at ODT, draws on expertise from a number of key companies working in the medical device space. Evonik’s Thiago Borges contributes with insights into RESOMER® PrintPowder for 3D printing.

Interview with Jane Meyer | March 11, 2022

With contributions from nearly 50 companies, this roundtable looks at which new technologies are emerging in the healthcare business, and the challenges and capabilities required to navigate and maximize the benefits of these technologies.

Interview with Jane Meyer | March 11, 2022

This year will be an exciting time for parenteral drug delivery at Evonik. In this roundtable, Jane Meyer describes the highlights anticipated for 2022: fueling the growth of nucleic acid therapies with the supply of lipids, formulation technologies, manufacturing and much more! 

by Stefan Randl and Maaike Everts, January 2022

The Covid-19 pandemic has ushered in a new era in medicine – that of mRNA technology. But the potential of mRNA for preventing and treating a whole range of diseases reaches further to infectious diseases, cancer immunotherapy and gene therapy.

by Gaelle Phillips, January 2021

COVID-19 has put biopharmaceuticals in the spotlight although business analysts had been awestruck by the meteoric rise of the industry for some time.

June 2021

Find out how to choose the right development partner and solution providers for your nutraceutical products!

by Gilles Razzauti, November 2021

Consumers are becoming more informed about their nutraceutical choices. They want more natural, organic, sustainable, pure and vegan products which are less processed and free from food additives or impurities.