by Dr. Martin Schilling | May 2023

Cell therapies based on mesenchymal stromal cells (MSCs) and T-cells (e.g. CAR-T cells) have become a commercial reality over the last decade, enabling a series of breakthroughs in patient care. In this article, Dr. Martin Schilling discusses how highly pure L-Carnosine can be used as a versatile booster for cell cultivation improvements.

by Nina Hauschildt & Miriam Robota | May 2023

For more than 70 years, innovations in the complex oral drug product industry have formed the foundation of modern medicine in a variety of applications. This article describes the role of functional polymers in the ability to control a drug’s release profile.

by Dr. Martin Schilling | May 2023

Cell culture processes are the technological foundation of the biopharmaceutical industry. The continued revolution in health care, driven by biological drugs has raised the importance of high-performing cell culture for the biopharmaceutical industry. This article is about how biopharmaceutical companies can ensure productivity, supply security, quality and consistency in their cell culture processes.

by Dr. Martin Schilling | April 2023

Chemically defined amino acids and their derivatives are often the preferred choice for use as components in cell culture media for biopharmaceuticals and vaccines. In this article, Dr. Martin Schilling discusses how dipeptides are evolving to match the performance, quality and processing needs of biopharma. 

by Andrea Engel |  March 2023

Evonik has just entered into a new collaborative research project to investigate new materials for RNA-based medicines. The three-year project is funded by the German Federal Ministry of Economic Affairs and Climate Action, who will support the research  with a two-digit million-euro sum. Find out more in this interview with Andrea Engel, head of Health Care growth projects at Evonik. 

by Yiming Ma |  June 2022

Spray-dried dispersion, hot-melt extrusion and solubilizing excipients are the most common techniques for solubility enhancement, but the pharmaceutical sector needs new innovations to maximize amorphous solid dispersion benefits. In this article, Yiming Ma discusses how microparticles can offer a potential extra avenue for successful solubility enhancement.

by Tom Tice & Whitney Moro | May 2022

Functional lactide/glycolide polymers play a key role in complex parenteral drug delivery products. In this article, two Evonik experts discuss the history and significance of polymer drug delivery, and what needs to be considered when formulating long-acting injectables.

Interview with Jochen Becker | February 2022

As the human impact on our environment continues to increase, all industries will need to act to reduce their environmental footprint, improve sustainability and live within the boundaries of our planet. In this interview, Jochen Becker talks about what this means for pharmaceutical manufacturing.  

Interview with Uwe Beekmann | April 19, 2022
MD+DI

Biosynthetic cellulose is a nature-identical material that is bioengineered by bacteria. In this article, Evonik’s Uwe Beekmann discusses the applications of this versatile material in wound dressings, implantable materials and drug delivery systems.

by Johanna Peters | April 19, 2022
Cell Culture Dish

Adeno-associated virus (AAV) vectors are a platform technology for gene therapies. As biopharmaceutical development progresses from clinical to commercial phases, there is an increasing need to improve the productivity of viral vector production processes. In this article, Johanna Peters discusses how cQrex® GQ can optimize the production yield and quality of viral vectors.

Interview with Jay Stone | April 2022

Many excipients are opening exciting opportunities for drug developers. One area of interest is the lipid drug delivery platforms used for transporting mRNA and nucleic acids. In this special report, experts from a range of companies provide their insight into how excipients are being used to support the APIs of today and tomorrow.

Interview with Thiago Borges | March 24, 2022

In this article on the application of additive manufacturing in complex orthopedic implants and components, Sam Brusco, Associate Editor at ODT, draws on expertise from a number of key companies working in the medical device space. Evonik’s Thiago Borges contributes with insights into RESOMER® PrintPowder for 3D printing.

Interview with Jane Meyer | March 11, 2022

With contributions from nearly 50 companies, this roundtable looks at which new technologies are emerging in the healthcare business, and the challenges and capabilities required to navigate and maximize the benefits of these technologies.

Interview with Jane Meyer | March 11, 2022

This year will be an exciting time for parenteral drug delivery at Evonik. In this roundtable, Jane Meyer describes the highlights anticipated for 2022: fueling the growth of nucleic acid therapies with the supply of lipids, formulation technologies, manufacturing and much more! 

by Stefan Randl and Maaike Everts, January 2022

The Covid-19 pandemic has ushered in a new era in medicine – that of mRNA technology. But the potential of mRNA for preventing and treating a whole range of diseases reaches further to infectious diseases, cancer immunotherapy and gene therapy.

by Gaelle Phillips, January 2021

COVID-19 has put biopharmaceuticals in the spotlight although business analysts had been awestruck by the meteoric rise of the industry for some time.

June 2021

Find out how to choose the right development partner and solution providers for your nutraceutical products!

by Gilles Razzauti, November 2021

Consumers are becoming more informed about their nutraceutical choices. They want more natural, organic, sustainable, pure and vegan products which are less processed and free from food additives or impurities. 

Chemical & Engineering News 
October 2020

This white paper explores opportunities to accelerate development workflows, optimize purity and yield, and reduce capital investment by applying modular approaches to the continuous manufacturing of APIs or advanced intermediates under cGMP conditions. 

CheManager
by Andreas Meuth, September 2020

The pharmaceutical industry is focusing increasingly on specialized drugs with new treatment modalities.  Behind these substances are pharmacologically active substances (HPAPIs) that develop their biological activity at extremely low concentrations. 

Pharmaceutical Technology
September 2020

Get information on a review of a modular aseptic filling platform for use with complex and personalized parenteral medications in powder, liquid, suspension or combination form!

August 2020

Successful nutraceutical manufacturers recognize that the right choice of ingredients and formulation services can make all the difference when it comes to brand preference and consumer acceptance.

Pharmaceutical Technology
by Felicity Thomas, June 2020

The global COVID-19 pandemic has underlined the need for the pharmaceutical industry to strengthen its supply chain enabling lower costs, efficient drug development and commercialization channels.

Pharmaceutical Technology
by Felicity Thomas, May 2020

Reformulation strategies can help formulators reduce product development times, increase patient adherence, enhance brand preference, and extend the commercial life cycle of the product by using proprietary formulation technologies that are difficult to copy by potential generic competitors.

by Lucia Heckler, April 2020

The old addage "you are what you eat" could equally be said for cell culture, because the quality of what you put into your bioreactor dictates the quality of what comes out. Discover how smart media formulations drive performance!

Drug Development & Delivery
April 2020

In this annual report, excipient manufacturers describe how their excipient offerings improve drug release, solubility, taste, physical properties, viscosity and more for a range of molecules.

Chemical & Engineering News
by Dr. Dana Kralisch, April 2020

Advanced technology platforms for defining pharma-CMO relationships enable the combination of advanced technologies for complex projects such as coupling HPAPI, catalysis, cyrogenic and organometallic technologies for high potency compounds that require a complex manufacturing process. 

Drug Development & Delivery Magazine
April 2020

The development of more functionalized and specialized drugs can optimize performance as well as safety and patient acceptance. Functional excipients can be used in a range of oral and parenteral dosage forms to achieve virtually any desired release profile. 

by Bente Jonassen, March 2020

If you are seeking to develop or enhance a nutraceutical product targeting a specific consumer group or application area, read on to find out how you can create preferred formulations which are highly accepted and preferentially used.

Drug Development & Delivery Magazine
March 2020

Stabilized amorphous solid dispersions (ASDs) are the most effective and widely used method for improving drug solubility, which can lead to higher bioavailability, especially when permeability is not the limiting factor. This is because in order to make an active ingredient bioavailable, a certain level of solubility in water must be achieved.

Speciality Chemicals Magazine 
by Dr. Tim Pohlmann, February 2020

Learn more about how a facility has been qualified to handle high-potency active pharmaceutical ingredients through industrial hygiene measures, risk management and a robust hazard assessment.

Teknoscienze (TKS)
January | February 2020

The article briefly reviews the emergence of lipid nanoparticle formulations of nucleic acids from liposomal systems and the differences in formulation and manufacturing practices that have enabled clinical application.

by Clarisse Binet-Gross, January 2020

Omega-3 fish oil supplements are becoming increasingly popular. However, processing fish oil into a convenient and palatable form is a major challenge and often results in consumers' needs not being met. Discover how we can help change that!

American Pharmaceutical Review
by Nadine Bremser, January 2020

It is an important regulatory and safety requirement that the potential hazards of handling HPAPIs be identified and understood to enable the development of occupational exposure limits (OELs). Therefore, we explain their manufacture with best practice safety and containment control procedures.