Health Care

Stories

Here you will find a selection of our articles and blogs. Please find out more about the latest trends, formulations and production in the life science industry. As science and technology are in a permanent state of motion.

Are you missing out on the benefits of microparticles for solubility enhancement?

by Yiming Ma |  June 2022

Spray-dried dispersion, hot-melt extrusion and solubilizing excipients are the most common techniques for solubility enhancement, but the pharmaceutical sector needs new innovations to maximize amorphous solid dispersion benefits. In this article, Yiming Ma discusses how microparticles can offer a potential extra avenue for successful solubility enhancement.

Is it time you knew more about biodegradable polymers for parenteral drug delivery?

by Tom Tice & Whitney Moro | May 2022

Functional lactide/glycolide polymers play a key role in complex parenteral drug delivery products. In this article, two Evonik experts discuss the history and significance of polymer drug delivery, and what needs to be considered when formulating long-acting injectables.

How can pharmaceutical manufacturing become greener?

Interview with Jochen Becker | February 2022

As the human impact on our environment continues to increase, all industries will need to act to reduce their environmental footprint, improve sustainability and live within the boundaries of our planet. In this interview, Jochen Becker talks about what this means for pharmaceutical manufacturing.  

Consider Biosynthetic Cellulose for Wound Management, Implants & Drug Delivery

Interview with Uwe Beekmann | April 19, 2022
MD+DI

Biosynthetic cellulose is a nature-identical material that is bioengineered by bacteria. In this article, Evonik’s Uwe Beekmann discusses the applications of this versatile material in wound dressings, implantable materials and drug delivery systems.

The cQrex® GQ effect: Boosting viral vector yield and quality in HEK-based AAV-production

by Johanna Peters | April 19, 2022
Cell Culture Dish

Adeno-associated virus (AAV) vectors are a platform technology for gene therapies. As biopharmaceutical development progresses from clinical to commercial phases, there is an increasing need to improve the productivity of viral vector production processes. In this article, Johanna Peters discusses how cQrex® GQ can optimize the production yield and quality of viral vectors.

Excipients: Exciting Expansion & Innovation 

Interview with Jay Stone | April 2022

Many excipients are opening exciting opportunities for drug developers. One area of interest is the lipid drug delivery platforms used for transporting mRNA and nucleic acids. In this special report, experts from a range of companies provide their insight into how excipients are being used to support the APIs of today and tomorrow.

Examining 3D Printing for Orthopedics - Additive manufacturing is finding its place in making complex orthopedic implants and components

Interview with Thiago Borges | March 24, 2022

In this article on the application of additive manufacturing in complex orthopedic implants and components, Sam Brusco, Associate Editor at ODT, draws on expertise from a number of key companies working in the medical device space. Evonik’s Thiago Borges contributes with insights into RESOMER® PrintPowder for 3D printing.

What is the key to being a leader in the industry? 

Interview with Jane Meyer | March 11, 2022

With contributions from nearly 50 companies, this roundtable looks at which new technologies are emerging in the healthcare business, and the challenges and capabilities required to navigate and maximize the benefits of these technologies.

What important company milestone do you anticipate reaching in 2022? 

Interview with Jane Meyer | March 11, 2022

This year will be an exciting time for parenteral drug delivery at Evonik. In this roundtable, Jane Meyer describes the highlights anticipated for 2022: fueling the growth of nucleic acid therapies with the supply of lipids, formulation technologies, manufacturing and much more! 

mRNA technology

Rewriting the health code

by Stefan Randl and Maaike Everts, January 2022

The Covid-19 pandemic has ushered in a new era in medicine – that of mRNA technology. But the potential of mRNA for preventing and treating a whole range of diseases reaches further to infectious diseases, cancer immunotherapy and gene therapy.

disruptive forces in biopharma

Seizing the opportunities from disruptive forces in biopharma

by Gaelle Phillips, January 2021

COVID-19 has put biopharmaceuticals in the spotlight although business analysts had been awestruck by the meteoric rise of the industry for some time.

the right solution providers for nutraceutical products

Your biggest formulation decision

June 2021

Find out how to choose the right development partner and solution providers for your nutraceutical products!

sustainable food without additives

Value through social responsibility

by Gilles Razzauti, November 2021

Consumers are becoming more informed about their nutraceutical choices. They want more natural, organic, sustainable, pure and vegan products which are less processed and free from food additives or impurities. 

manufacturing of APIs

Continuous manufacturing of APIs 

Chemical & Engineering News 
October 2020

This white paper explores opportunities to accelerate development workflows, optimize purity and yield, and reduce capital investment by applying modular approaches to the continuous manufacturing of APIs or advanced intermediates under cGMP conditions. 

manufacturing of HPAPIs

Requirements of Safe HPAPI Manufacturing 

CheManager
by Andreas Meuth, September 2020

The pharmaceutical industry is focusing increasingly on specialized drugs with new treatment modalities.  Behind these substances are pharmacologically active substances (HPAPIs) that develop their biological activity at extremely low concentrations. 

modular aseptic filling platform

Aseptic filling of powder, liquid suspension and combination forms

Pharmaceutical Technology
September 2020

Get information on a review of a modular aseptic filling platform for use with complex and personalized parenteral medications in powder, liquid, suspension or combination form!

formulations for nutraceutical manufacturers

Top ten tips on formulation opportunities 

August 2020

Successful nutraceutical manufacturers recognize that the right choice of ingredients and formulation services can make all the difference when it comes to brand preference and consumer acceptance.

strenghtening of supply chains in the pharmaceutical industry

Securing the Supply Chain

Pharmaceutical Technology
by Felicity Thomas, June 2020

The global COVID-19 pandemic has underlined the need for the pharmaceutical industry to strengthen its supply chain enabling lower costs, efficient drug development and commercialization channels.

reformulation technologies in the pharmaceutical industry

A Welcome Change: The Benefits of Reformulation

Pharmaceutical Technology
by Felicity Thomas, May 2020

Reformulation strategies can help formulators reduce product development times, increase patient adherence, enhance brand preference, and extend the commercial life cycle of the product by using proprietary formulation technologies that are difficult to copy by potential generic competitors.

cell culture

New opportunities for consumer convenience

by Lucia Heckler, April 2020

The old addage "you are what you eat" could equally be said for cell culture, because the quality of what you put into your bioreactor dictates the quality of what comes out. Discover how smart media formulations drive performance!

impovement of drug viscosity and solubility

Excipients: matching ingredients to molecules improves functionality

Drug Development & Delivery
April 2020

In this annual report, excipient manufacturers describe how their excipient offerings improve drug release, solubility, taste, physical properties, viscosity and more for a range of molecules.

APIs for defining pharma-CMO relationships

Advanced technology platforms 

Chemical & Engineering News
by Dr. Dana Kralisch, April 2020

Advanced technology platforms for defining pharma-CMO relationships enable the combination of advanced technologies for complex projects such as coupling HPAPI, catalysis, cyrogenic and organometallic technologies for high potency compounds that require a complex manufacturing process. 

development of more functionalized and specialized drugs

EXCIPIENTS: MATCHING INGREDIENTS TO MOLECULES IMPROVES FUNCTIONALITY

Drug Development & Delivery Magazine
April 2020

The development of more functionalized and specialized drugs can optimize performance as well as safety and patient acceptance. Functional excipients can be used in a range of oral and parenteral dosage forms to achieve virtually any desired release profile. 

preferred formulations for nutraceutical products

Brand loyalty: customer convenients trends

by Bente Jonassen, March 2020

If you are seeking to develop or enhance a nutraceutical product targeting a specific consumer group or application area, read on to find out how you can create preferred formulations which are highly accepted and preferentially used.

improvement of bioavailability and solubility

Improving Bioavailability & Solubility: Understand Your Molecule

Drug Development & Delivery Magazine
March 2020

Stabilized amorphous solid dispersions (ASDs) are the most effective and widely used method for improving drug solubility, which can lead to higher bioavailability, especially when permeability is not the limiting factor. This is because in order to make an active ingredient bioavailable, a certain level of solubility in water must be achieved.

handling of active pharmaceutical ingredients

Qualification of a small-scale facility for ultra-HPAPIs

Speciality Chemicals Magazine 
by Dr. Tim Pohlmann, February 2020

Learn more about how a facility has been qualified to handle high-potency active pharmaceutical ingredients through industrial hygiene measures, risk management and a robust hazard assessment.

lipid nanoparticle mediated gene therapy

LIPID NANOPARTICLE MEDIATED GENE THERAPY

Teknoscienze (TKS)
January | February 2020

The article briefly reviews the emergence of lipid nanoparticle formulations of nucleic acids from liposomal systems and the differences in formulation and manufacturing practices that have enabled clinical application.

natural products like omega-3 fish oil supplements

Natural products for the satisfaction of consumer preferences

by Clarisse Binet-Gross, January 2020

Omega-3 fish oil supplements are becoming increasingly popular. However, processing fish oil into a convenient and palatable form is a major challenge and often results in consumers' needs not being met. Discover how we can help change that!

handling and understanding of HPAPIs

Manufacturing of Highly Potent APIs 

American Pharmaceutical Review
by Nadine Bremser, January 2020

It is an important regulatory and safety requirement that the potential hazards of handling HPAPIs be identified and understood to enable the development of occupational exposure limits (OELs). Therefore, we explain their manufacture with best practice safety and containment control procedures.

Archive of publications

Manufacturing of highly potent APIs with best-practice safety and containment control procedures

American Pharmaceutical Review , September | October 2019

Panel Discussion on Flow Chemistry

Tekno Scienze Publisher, May | June 2019

Development of a continuous process for organometallic reactions - a perspective

Tekno Scienze Publisher, May | June 2019

Drug Delivery Roundtable

Americal Pharmaceutical Review, October 2019

The Fundamentals of Dissolution Testing

PharmTech, October 2019

Selecting a Solid Approach

PharmTech, July 2019

Excipients: Formulators Want Excipients for Solubility & Beyond

Drug Development & Delivery, April 2019

Improving Bioavailability & Solubility: Chemical & Physical Modification vs. Formulation Development

Drug Development & Delivery, March 2019

Drug Delivery Roundtable

Americal Pharmaceutical Review, October 2019

Outsourcing Formulation Development & Manufacturing: CDMOs Shift to Offer More Specialized Services

Drug Development & Delivery, June 2019

An Interview with Danielle Clay, Director of Global Strategic Marketing and Business Development for Injectable Drug Delivery, Evonik

American Pharmaceutical Review, February 2019

Evonik Completes Multi-Million Dollar Expansion of its CMO Capabilities for API & Advanced Intermediates

Drug Development & Delivery, September 2018

Evonik Expands CMO Capabilities for APIs and Intermediates

PharmTech, September 2018

Cultural change in the Midwest - Evonik claims success in turning a Lilly drug plant into a pharmaceutical services facility

Chemical & Engineering News, March 2018

Continuous flow development

Pharma and Chemical Industry, February 2018

Evonik Launches Advanced Combination Polymer for Enteric Coatings

PharmTech, October 2018

Evonik Launches EUDRAGIT FL 30 D-55

American Pharmaceutical Review, October 2018

Coating for Tastemasking

PharmTech, September 2018

Improving Bioavailability & Solubility: A Top-Down Versus Bottom-Up Approach

Drug Development & Delivery, March 2018

Evonik Expands North American Contract Development & Manufacturing Capabilities for Advanced Injectables

Drug Development & Delivery, August 2018

Outsourcing Formulation Development & Manufacturing: CDMOs Are Innovating for 21st-Century Medicine

Drug Development & Delivery, June 2018

Development and implementation of a large-scale HPAPI manufacturing process

Tekno Scienze Publisher, September | October 2017

Evonik Industries and Eli Lilly renew agreement

Manufacturing Chemist, November 2017

Advanced approaches for delayed-release formulations

OnDrugDelivery Magazine, July 2017

Trends in Excipient Demand

Pharmaceutical Manufacturing, June 2017

Developing dosage forms

WorldPharma, January 2017

A 30-Year History of PLG Applications in Parenteral Controlled Drug Release

PharmTech, July 2017

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