EUDRATEC® COL - Colonic drug delivery
Improve efficacy by drug targeting.
What is EUDRATEC® COL?
EUDRATEC® COL is an oral drug delivery technology for multiple-unit dosage forms
Designed for colon targeting
pH-triggered, sustained-release profiles are achieved by first coating the API core with a sustained-release EUDRAGIT® polymer followed by a second pH-dependent soluble coating, e.g. EUDRAGIT® FS 30 D
What is the application?
Reduction of daily intake
Local treatment of colonic diseases such as inflammatory bowel diseases or colon cancer
Systemic delivery for drugs with absorption in colon
What makes EUDRATEC® COL unique?
Advanced release profiles can be designed using conventional technologies and registered polymers
Coated pellets can be filled into capsules and compressed into multiparticulate tablets
Concept was proven in-vivo