cQrex™ Cell culture ingredients

For research, manufacturing and clinical applications.

cQrex™ - The Evonik brand for cell culture solutions with scientifically proven benefits

As one of the world leaders in specialty chemicals, Evonik provides the global cell culture industry with a portfolio of highly purified amino acids, chemically defined boosters, customized media ingredients and application services under its cQrex™ brand.

In addition to being animal-origin free and controlled for impurities to achieve the highest product quality, the portfolio is designed to enhance media formulation flexibility, improve cell culture performance and reduce process risks and costs.

With our expertise in cGMP, we also offer in-house manufacturing with an excellent degree of backward integration and highest purity standards to guarantee reproducibility.

Our qualification in a nutshell:

Animal origin free – guaranteed
cGMP compliance, ISO certification (9001, 14001)
Positive track record for inspections, from customers to authorities (FDA, ANSM)
Experienced and qualified staff
Full support from R&D to production and clinical application
The ideal combination of chemical and biotechnological expertise with the stability and staying power of a global player

And don't forget: all products are available from lab to production scale.

CQREX™ SAMPLE KIT

Are you interested in our products and would like to order a sample kit of cQrex™ cell culture ingredients?
It allows you to test our substances in your system, as no cell line is quite the same.

A combination of our current line-up of boosters is gathered in one kit. You are looking for something else besides our standard amino acids? Individual samples can be supplied upon request.

Get in contact with our experts or sign in to our onCare web portal to order a sample kit.

Amino acids & amino acid salts
	CAS No	GMP grade
L-Alanine	56-41-7	ο
L-Asparagine monohydrate	5794-13-8	ο
L-Aspartic acid	56-84-8	ο
L-Glutamic acid	56-86-0	ο
Glycine	56-40-6	ο
L-Isoleucine	73-32-5	ο
L-Leucine	61-90-5
L-Lysine monohydrate	39665-12-8	ο
L-Methionine	63-68-3	ο
L-Proline	147-85-3	ο
L-Serine	56-45-1	ο
L-Threonine	72-19-5	ο
L-Tryptophan	73-22-3	ο
L-Valine	72-18-4	ο
L-Arginine-L-aspartate	7675-83-4	ο
L-Lysine-L-aspartate	27348-32-9
L-Lysine hydrochloride	657-27-2	ο
L-Lysine-L-glutamate dihydrate	5408-52-6	ο
L-Lysine-L-malate	71555-10-7	ο

Chemically defined boosters

GMP grade peptides and keto acids solving key issues in mammalian cell culture.

Dipeptides for solubility

cQrex™ GY, a L-Tyrosine containing peptide, offers high solubility at neutral pH without introducing new substances to the medium and is readily metabolized.

Dipeptides for stability

cQrex™, cQrex™ AQ and GQ stabilize the amino acid, leading to longer shelf life and improved cultivation performance.

Keto-acids for performance

cQrex™ AKG directly stimulates the energy cycle without ammonia generation and acts as scavenger for ammonia and oxidants, boosting cell density and titer levels.

For detailed Information please also check our cQrex™ brochure.

cQrex™ boosters are designed to create value in cell culture applications in regards to consistency, risk reduction and cost improvements.

Boosters
	GMP grade
cQrex™ AQ (L-Alanyl-L-Glutamine)	ο
cQrex™ GQ (Glycyl-L-Glutamine monohydrate)	ο
cQrex™ GY (Glycyl-L-Tyrosine dihydrate)	ο
cQrex™ AAQ (N-Acetyl-L-Alanyl-L-Glutamine)
L-Alanyl-L-Proline
cQrex™ AKG (a-Ketoglutaric acid)	ο
cQrex™ HSE (L-Homoserine)

When you need a little extra

A new ingredient may work wonders in your process, but what’s the use if it’s not available with precisely the same characteristics and properties at the volume production scale.

Do you need a peptide?
Evonik Health Care’s flexible dipeptide technology can match virtually almost any need – up to metric ton scale.
Do you need a non-natural amino acid as linker in your mAB?
Count on our expertise in chemistry and biotechnology to identify a fast and efficient process design.
Your desired ingredient is not an amino acid?
Take advantage of our decades-long experience in chemical and pharmaceutical custom manufacturing – we can develop and scale up almost any compound.

Whatever it is, rest assured that it is in good hands with one of the biggest and most respected players in industrial biotechnology and custom synthesis.

Supporting you all the way from development to regulatory approval

Great service can mean a lot of things, but it needs to make life easier for you. And that means

Supporting you in finding the right combination of media and boosters to make sure you get the most out of your cells.
Providing you with custom solutions from special products to special packaging, including 1 kg bags.
Being at your side up to regulatory approval, putting our deep understanding of regulatory demands and frameworks at your disposal.

For further service information, please have a look at our cell culture ingredients brochure.