Immediate release

Delayed release


Polymers for enteric release.


When a drug must be protected from the gastric fluids in the stomach’s acidic environment until it reaches the intestine for delivering maximum efficacy, EUDRAGIT® L and S polymers are the preferred choice of coating polymers.

Part of a broad family of anionic EUDRAGIT® grades that only dissolve above a specific trigger pH, these polymers enable formulators to target specific areas of the intestine. They can also be combined with each other to dial in a specific dissolution pH for additional precision in gastrointestinal targeting.

EUDRAGIT® offers key benefits for your enteric coatings:
  • Gastro resistance

  • pH-controlled drug release

  • Gastrointestinal targeting

  • Colon delivery

  • Protection of acid-sensitive actives

  • Protection of gastric mucosa from aggressive actives

  • Increased drug effectiveness

  • Excellent storage stability

Boost efficiency with PlasACRYL®

Designed specifically with EUDRAGIT® polymers in mind PlasACRYL® is an easy-to-use additive that improves coating efficiency and reduces processing times. It is available in two grades: PlasACRYL® HTP 20 for EUDRAGIT® L 30 D-55 applications and PlasACRYL® T20 for use in EUDRAGIT® FS 30 D coatings. Both grades consist of 20 percent aqueous suspensions with glycerol monostearate as anti-tacking agent, TEC as plasticizer and stabilizer. With PlasACRYL® lowering production costs has never been easier.

Product

Availability

Dissolution property

EUDRAGIT® 
L 100-55

Powder

Dissolution above pH 5.5

EUDRAGIT®
L 30 D-55

Aqueous dispersion

PlasACRYL® HTP 20

Easy-to-use glidant and plasticizer premix, specifically designed for
EUDRAGIT® L 30 D-55 formulations

EUDRAGIT® L 100

Powder

Dissolution above pH 6.0

EUDRAGIT® L 12,5

Organic solution

EUDRAGIT® S 100

Powder

Dissolution above pH 7.0

EUDRAGIT® S 12,5

Organic solution

EUDRAGIT® FS 100

Powder

EUDRAGIT® FS 30 D

Aqueous dispersion

PlasACRYL® T20

Easy-to-use glidant and plasticizer premix, specifically
designed for EUDRAGIT® FS 30 D formulations

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chematic® cleaner

Cleaning your equipment after processing EUDRAGIT® L, FS & S formulations can be an efficient and safe process.

Special detergents have been developed by Dober, USA, in close cooperation with Evonik. Chematic Cleaners provide optimized cleaning results with minimum efforts.

Benefits:
  • For WIP and CIP processes

  • For manual cleaning

  • Mild chemistry

  • Low processing temperature.

 

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