Keto acids are used as active pharmaceutical ingredients to support the treatment and medication of patients with chronic kidney disease (CKD). Their role is to relieve the build-up of nitrogenous waste and other toxic substances inside the body. Evonik is not only the world’s largest manufacturer of keto acids but has also earned a strong track record of performance for the supply of these active pharmaceutical ingredients at the highest levels of quality and purity. Through our established manufacturing facilities for keto acids in Germany and China, we can support customers in the supply of all five keto acids and other amino acids used for CKD treatment drugs.

L-Ornithine-L-Aspartate (LOLA) has been used as an active pharmaceutical ingredient for the treatment of liver diseases for many decades. Evonik’s brand of L-Ornithine-L-Aspartate utilizes a highly efficient purification process to ensure low methanol content and endotoxin levels. Due to its high purity, the API can also generate superior stability. Furthermore, it has excellent uniform particle-size distribution as well as a crystalline structure compared to some other products on the market.