Generic active pharmaceutical ingredients (API) in the quality and purity you need

Optimizing the quality, purity and supply security of your active pharmaceutical ingredients (APIs) has never been more important.  At Evonik, our range of generic APIs is backed by an unrivalled track record for quality, reliability and safety. We can draw on decades of experience, state-of-the-art manufacturing capabilities and a truly global network, so you can be sure you are getting consistently outstanding generic APIs.

We provide customers worldwide with a broad portfolio of generic APIs including keto acids:

Keto acids are used as active pharmaceutical ingredients to support the treatment and medication of patients with chronic kidney disease (CKD). Their role is to relieve the build-up of nitrogenous waste and other toxic substances inside the body. Evonik is not only the world’s largest manufacturer of keto acids but has also earned a strong track record of performance for the supply of these active pharmaceutical ingredients at the highest levels of quality and purity. Through our established manufacturing facilities for keto acids in Germany and China, we can support customers in the supply of all five keto acids and other amino acids used for CKD treatment drugs.

L-Ornithine-L-Aspartate (LOLA) has been used as an active pharmaceutical ingredient for the treatment of liver diseases for many decades. Evonik’s brand of L-Ornithine-L-Aspartate utilizes a highly efficient purification process to ensure low methanol content and endotoxin levels. Due to its high purity, the API can also generate superior stability. Furthermore, it has excellent uniform particle-size distribution as well as a crystalline structure compared to some other products on the market.

In addition to the cGMP manufacturing of active pharmaceutical ingredients at our trusted sites in Europe and Asia, we also provide customers with a broad array of regulatory services to support their process validation and document submissions activities.

All key certifications utilized with active pharmaceutical ingredients are also available including those required for GMP compliance, non-GMO products, kosher and halal certification, BSE / TSE and the use of non-animal origin materials.

Our Generic API Product List

Product name

CAS Number




846-49 -1

α-Hydroxymethionine, Calcium salt


α-Ketoisoleucine, Calcium salt


α-Ketoleucine, Calcium salt


α-Ketophenylalanine, Calcium salt


α-Ketovaline, Calcium salt


For more information on our portfolio of generic APIs and pharmaceutical intermediates please follow the links below or contact us directly.

Learn more about Evonik's portfolio of generic APIs & pharmaceutical intermediates